What, Exactly, is CBD?
CBD is a component of the cannabis plant that is used medically. CBD is non-psychoactive, which means it does not make you feel high. It does not affect your brain or central nervous system, unlike THC. CBD is also safe and legal to use, even in states where medical marijuana is still illegal.
What Are Cannabinoids?
Cannabinoids are a class of naturally occurring compounds that have a wide range of physiological effects. Cannabinoids influence neurotransmitter release and may even have immunomodulatory properties. Cannabis' unusual combination of phytocannabinoids and other compounds offers many health benefits in addition to its well-known ability to reduce and inhibit pain.
Cannabinoids were discovered in the 1940s, and their endogenous properties in the brain and throughout the central nervous system were discovered in the mid-1980s. Cannabinoids are now known to exist in both the plant and animal kingdoms. Cannabinoids found in PCR hemp include CBD, CBN, and CBC.
What is the role of endocannabinoids?
The endocannabinoid system is a network of various receptors found mainly within the brain and central nervous system. Because it responds to changes in cells and communication, the collection of cells and receptors is known as a signaling system.
For the brain to control the body's various functions, it uses endocannabinoids, a unique set of molecules that, similar to traffic signals, connect with specific sites in the brain or other body tissues. In each area in which cannabinoids are found, they have special instructions regarding acting to achieve a particular outcome. For example, some cannabinoids reduce inflammation, while others encourage us to eat more, and still, others can increase pain perception.
Our endocannabinoids do many things, and scientists continue to unravel their roles in helping to maintain a healthy body. For example, the ECS plays a role in transmitting messages through the body's nervous system, relaying information about pain, mood, memory, appetite and more. These messages affect our organs and tissues, and the immune system, which protects us from disease.
The Human Endocannabinoid System (ECS)
The Human Endocannabinoid System (ECS) is a master regulatory system controlling the functionality of our bodies. The ECS comprises two unique receptor systems, CB1 and CB2, attached to every major organ and tissue inside the body. These receptors are activated by compounds present in the cannabis plant, called phytocannabinoids. Phytocannabinoids interact with these receptors to produce changes in the body.
For example, anandamide is a neurotransmitter that plays a role in the brain's endocannabinoid system. Anandamide is responsible for producing and removing serotonin in the body. Serotonin is known as the "bliss molecule" because its high amounts are associated with a positive mood. In addition, serotonin helps to regulate memory, sleep, appetite, pain, and more.
The Entourage Effect
The "entourage effect" is a hypothesis that the combined effects of the several components present in a natural cannabis plant working together are therapeutically superior to the isolated effects of any one individual component, such as cannabidiol (CBD). The hypothesis draws on concepts of botany and pharmacology, suggesting that naturally occurring chemical compounds found in the cannabis plant act together to induce certain effects, which may be more effective than those induced by any single compound alone. Therefore CBD is more effective when it includes trace amounts of THC, terpenes and other cannabinoids.